Bayesian Adaptive Approaches in Rare and Pediatric Disease
On Demand
1 hour 12 minutes
Your Desk!
REGISTER NOW
Speakers
Bradley P. Carlin
Senior Advisor Data Science and Statistics, PharmaLex
Key learning objectives:
Brief review of Complex Innovative Trial Designs (CIDs) and role of Bayesian adaptive methods
Importance in rare and pediatric disease; need to deal with small sample sizes and low power using traditional methods
Use of power, commensurate, robust mixture prior methods to cautiously borrow strength from historical controls and other auxiliary data, including natural history studies
Exemplification across a wide range of rare and pediatric settings